BIOL301 Prostate Cancer Study Paper
BIOL301 American College of California Prostate Cancer Study Paper
Assignment “Patient Scenario “
Mr. Smith is 60 years old. He was diagnosed with a prostate cancer five years ago. Over the past few days, Mr. Smith has been feeling weak and increasingly tired and has also been suffering from a headache that did not respond to over-the-counter medications. He scheduled an appointment with his physician.
His physician performed a physical examination and recommended a battery of laboratory tests and imaging procedures.
The table below shows Reference values in the right-hand column. These values reflect the normal range of values for patients without disease or illness. The center column reflects the resulting values for medical test results obtained for Mr. Smith.
Take note whether Mr. Smith’s values are within normal limits.
Mr. Smith | Reference Values | |
K+ | 2.6 mmol/L | 3.8-4.9mmol/L |
Hb (Hemoglobin) | 7.5 g/dL | 13.8 to 18.2 g/dL |
Hct (Hematocrit) | 20.4% | 45-52% |
Platelet Count | 49×109/L | 150-400×109/L |
BIOL301 Prostate Cancer Study Paper
After receiving Mr. Smith’s test results, his physician admits him to the hospital. Hospital staff treated him and discharged him.
The following week, Mr. Smith returns to his physician with the same complaint of weakness and a new complaint of shortness of breath. His blood pressure is 160/100 mmHg. MRI reveals metastasis of prostate cancer to osseous tissue. Abdominal CT shows obstruction of intestine due to nodular enlargement of adrenal glands.
BIOL301 American College of California Prostate Cancer Study Paper
Laboratory results from Mr. Smith’s second hospital admission and medical tests show following findings:
Mr. Smith | Reference Values | |
K+ | 2.6 mmol/L | 3.8-4.9mmol/L |
Hb | 7.3 g/dl | 13.8 to 18.2 g/dL |
Hct | 20.4% | 45-52% |
Platelet Count | 20×109/L | 150-400×109/L |
HCO3 | 38 mmol/l | 22-26 mmol/L |
Urinary K+ | 70 mmol/L/24 hr | 25-120 mmol/L/24 hr |
Blood Glucose | 460 mg/dl | 64.8-104.4 mg/dL |
Serum Aldosterone | 1 ng/dl | <31 ng/dL |
24 hour Urinary Aldosterone | 8.4 mcg/24 hr | 2.3-21.0 mcg/24 hr |
Renin | 2.1 ng/ml/hr | 0.65-5.0 ng/ml/hr |
ACTH (Adrenocorticotropic Hormone) | 1082 pg/ml | 9-46 pg/ml |
Cortisol | 155.5 microg/dL | 0-25 microg/dL |
BIOL301 Prostate Cancer Study Paper
CONCLUSION AND DIAGNOSIS
Laboratory findings, MRI and CT confirmed metastatic prostate adenocarcinoma, hypertension and refractory hypokalemia due to ectopic ACTH production. High levels of circulating cortisol caused continuous activation of mineralocorticoid receptors resulting in hypokalemia, metabolic alkalosis and hypertension.
After reading provided scenario, answer the following questions:
You should write a short paper addressing all six questions and submit it into the assignment folder. Your grade will depend upon the content, clarity and originality of responses written in your own words. Good writing practices, including the use of correct grammar, sentence and paragraph structure, and punctuation, and presence of logical reasoning, will account for a portion of your grade.
Cite all sources in APA format within your answer text as well as full citations in APA format at the end of the assignment.
BIOL301 Prostate Cancer Cancer Study Paper